FV News: The first cloned monkeys

January 24, 2018 - SHANGAI, China

The first primate clones made by Somatic Cell Nuclear Transfer (SCNT) are two genetically-identical long-tailed macaques born recently at the Institute of Neuroscience of Chinese Academy of Sciences in Shanghai. Researchers named the newborns "Zhong Zhong" and "Hua Hua" after the Chinese adjective "Zhōnghuá", which means Chinese nation or people. The research has been published on Wednesday, January 24, 2018 in the journal Cell.

The first cloned monkeys

«Generation of genetically uniform non-human primates may help to establish animal models for primate biology and biomedical research. In this study, we have successfully cloned cynomolgus monkeys (Macaca fascicularis) by somatic cell nuclear transfer (SCNT). (...) For SCNT using fetal monkey fibroblasts, 6 pregnancies were confirmed in 21 surrogates and yielded 2 healthy babies. For SCNT using adult monkey cumulus cells, 22 pregnancies were confirmed in 42 surrogates and yielded 2 babies that were short-lived. (...) Cloning of animals by somatic cell nuclear transfer (SCNT) has been achieved in 23 mammalian species including sheep, mouse, cattle, pig, cat, rat, and dog. As species closer to humans, non-human primates are ideal animal models for studying physiological functions unique to primates and for developing therapeutic treatments of human diseases».

Zhong Zhong and Hua Hua